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Target
D(3) dopamine receptor
Ligand
BDBM50226015
Substrate
n/a
Meas. Tech.
ChEMBL_458713 (CHEMBL942048)
EC50
>1000±n/a nM
Citation
 Blagg, J; Allerton, CM; Batchelor, DV; Baxter, AD; Burring, DJ; Carr, CL; Cook, AS; Nichols, CL; Phipps, J; Sanderson, VG; Verrier, H; Wong, S Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route. Bioorg Med Chem Lett 17:6691-6 (2007) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50226015
Synonyms:
1-(2-hydroxy-5-(4-propylmorpholin-2-yl)phenyl)ethanone | CHEMBL249588
Type:
Small organic molecule
Emp. Form.:
C15H21NO3
Mol. Mass.:
263.3321
SMILES:
CCCN1CCOC(C1)c1ccc(O)c(c1)C(C)=O |w:7.9|
Structure:
Search PDB for entries with ligand similarity: