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Target
Fatty acid-binding protein, heart
Ligand
BDBM50248245
Substrate
n/a
Meas. Tech.
ChEMBL_566943 (CHEMBL964126)
IC50
>10000±n/a nM
Citation
 Barf, T; Lehmann, F; Hammer, K; Haile, S; Axen, E; Medina, C; Uppenberg, J; Svensson, S; Rondahl, L; Lundbäck, T N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg Med Chem Lett 19:1745-8 (2009) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50248245
Synonyms:
5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid | CHEMBL516023
Type:
Small organic molecule
Emp. Form.:
C22H22N2O3
Mol. Mass.:
362.4217
SMILES:
NC(=O)c1cccc(Cn2c3CCCCCc3c3cccc(C(O)=O)c23)c1
Structure:
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