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Target
Beta-2 adrenergic receptor
Ligand
BDBM50287798
Substrate
n/a
Meas. Tech.
ChEBML_38465
Ki
13900±n/a nM
Citation
 Fisher, LG; Sher, PM; Skwish, S; Michel, IM; Seiler, SM; Dickinson, KE BMS-187257, a potent, selective, and novel heterocyclic β3 adrenergic receptor agonist Bioorg Med Chem Lett 6:2253-2258 (1996)    Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50287798
Synonyms:
4-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-thiazol-5-yl)-butyric acid | CHEMBL72168
Type:
Small organic molecule
Emp. Form.:
C18H23ClN2O3S
Mol. Mass.:
382.905
SMILES:
C[C@H](Cc1ncc(CCCC(O)=O)s1)NCC(O)c1cccc(Cl)c1
Structure:
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