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Target
Histone deacetylase-like amidohydrolase
Ligand
BDBM50293704
Substrate
n/a
Meas. Tech.
ChEMBL_571663 (CHEMBL1031318)
IC50
600±n/a nM
Citation
 Riester, D; Hildmann, C; Haus, P; Galetovic, A; Schober, A; Schwienhorst, A; Meyer-Almes, FJ Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases. Bioorg Med Chem Lett 19:3651-6 (2009) [PubMed]  Article 
Target
Name:
Histone deacetylase-like amidohydrolase
Synonyms:
HDAH_ALCSD | hdaH | hdaH1
Type:
PROTEIN
Mol. Mass.:
39419.78
Organism:
Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188))
Description:
ChEMBL_827139
Residue:
369
Sequence:
MAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLHALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADIR
  
Inhibitor
Name:
BDBM50293704
Synonyms:
1,1,1-trifluoro-7-(1H-naphtho[2,3-d]imidazol-2-yl)heptan-2-one | CHEMBL550625
Type:
Small organic molecule
Emp. Form.:
C18H17F3N2O
Mol. Mass.:
334.3356
SMILES:
FC(F)(F)C(=O)CCCCCc1nc2cc3ccccc3cc2[nH]1
Structure:
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