Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50257051
Substrate
n/a
Meas. Tech.
ChEMBL_644535 (CHEMBL1211412)
Ki
2800±n/a nM
Citation
 Cheng, F; Xu, Z; Liu, G; Tang, Y Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. Eur J Med Chem 45:3459-71 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50257051
Synonyms:
2-(6-amino-8-bromo-9H-purin-9-yl)ethanol | 8-Bromo-9-(2-hydroxyethyl)-9H-adenine | CHEMBL474058
Type:
Small organic molecule
Emp. Form.:
C7H8BrN5O
Mol. Mass.:
258.075
SMILES:
Nc1ncnc2n(CCO)c(Br)nc12
Structure:
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