Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50126867
Substrate
n/a
Meas. Tech.
ChEMBL_46984 (CHEMBL658954)
Ki
>1000±n/a nM
Citation
 López-Rodríguez, ML; Viso, A; Ortega-Gutiérrez, S; Fowler, CJ; Tiger, G; de Lago, E; Fernández-Ruiz, J; Ramos, JA Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. J Med Chem 46:1512-22 (2003) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50126867
Synonyms:
CHEMBL291021 | Icosa-5,8,11,14-tetraenoic acid bis-thiophen-2-ylmethyl-amide
Type:
Small organic molecule
Emp. Form.:
C30H41NOS2
Mol. Mass.:
495.783
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)N(Cc1cccs1)Cc1cccs1
Structure:
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