Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50172553
Substrate
n/a
Meas. Tech.
ChEMBL_320852 (CHEMBL884777)
Ki
1.91±n/a nM
Citation
 Deng, H; Gifford, AN; Zvonok, AM; Cui, G; Li, X; Fan, P; Deschamps, JR; Flippen-Anderson, JL; Gatley, SJ; Makriyannis, A Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. J Med Chem 48:6386-92 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50172553
Synonyms:
CHEMBL68641 | [1-(1-Methyl-piperidin-2-ylmethyl)-1H-indol-3-yl]-naphthalen-1-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C26H26N2O
Mol. Mass.:
382.4974
SMILES:
CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
Structure:
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