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Target
Metabotropic glutamate receptor 4
Ligand
BDBM50034501
Substrate
n/a
Meas. Tech.
ChEMBL_467215 (CHEMBL928086)
EC50
>1000000±n/a nM
Citation
 Pinto, A; Conti, P; De Amici, M; Tamborini, L; Madsen, U; Nielsen, B; Christesen, T; Bräuner-Osborne, H; De Micheli, C Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid. J Med Chem 51:2311-5 (2008) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a
Type:
Enzyme
Mol. Mass.:
101849.79
Organism:
Rattus norvegicus (Rat)
Description:
P31423
Residue:
912
Sequence:
MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM50034501
Synonyms:
(S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | (S)-Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic acid | CHEMBL30285
Type:
Small organic molecule
Emp. Form.:
C5H6N2O4
Mol. Mass.:
158.1121
SMILES:
N[C@H](C(O)=O)c1cc(=O)[nH]o1
Structure:
Search PDB for entries with ligand similarity: