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Target
Urotensin-2
Ligand
BDBM50164424
Substrate
n/a
Meas. Tech.
ChEMBL_643307 (CHEMBL1177478)
EC50
1122.02±n/a nM
Citation
 Lehmann, F; Currier, EA; Olsson, R; Ma, JN; Burstein, ES; Hacksell, U; Luthman, K Optimization of isochromanone based urotensin II receptor agonists. Bioorg Med Chem 18:4844-54 (2011) [PubMed]  Article 
Target
Name:
Urotensin-2
Synonyms:
UTS2 | UTS2_HUMAN
Type:
PROTEIN
Mol. Mass.:
14297.49
Organism:
Homo sapiens (Human)
Description:
ChEMBL_643307
Residue:
124
Sequence:
MYKLASCCLLFIGFLNPLLSLPLLDSREISFQLSAPHEDARLTPEELERASLLQILPEMLGAERGDILRKADSSTNIFNPRGNLRKFQDFSGQDPNILLSHLLARIWKPYKKRETPDCFWKYCV
  
Inhibitor
Name:
BDBM50164424
Synonyms:
3-(4-Chloro-phenyl)-3-(2-dimethylamino-ethyl)-isochroman-1-one | 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one | CHEMBL192359
Type:
Small organic molecule
Emp. Form.:
C19H20ClNO2
Mol. Mass.:
329.821
SMILES:
CN(C)CCC1(Cc2ccccc2C(=O)O1)c1ccc(Cl)cc1
Structure:
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