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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50022542
Substrate
n/a
Meas. Tech.
ChEMBL_1466693 (CHEMBL3404291)
IC50
2400±n/a nM
Citation
 Zhang, X; Raghavan, S; Ihnat, M; Hamel, E; Zammiello, C; Bastian, A; Mooberry, SL; Gangjee, A The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents. Bioorg Med Chem 23:2408-23 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50022542
Synonyms:
CHEMBL3297898 | US10189853, Compound 1
Type:
Small organic molecule
Emp. Form.:
C16H17N3O2
Mol. Mass.:
283.3251
SMILES:
COc1ccc(cc1)N(C)c1nc(C)nc2oc(C)cc12
Structure:
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