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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50073527
Substrate
n/a
Meas. Tech.
ChEMBL_1469711 (CHEMBL3413249)
IC50
880000±n/a nM
Citation
 Khattab, SN; Abdel Moneim, SA; Bekhit, AA; El Massry, AM; Hassan, SY; El-Faham, A; Ali Ahmed, HE; Amer, A Exploring new selective 3-benzylquinoxaline-based MAO-A inhibitors: design, synthesis, biological evaluation and docking studies. Eur J Med Chem 93:308-20 (2015) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_BOVIN | Amine oxidase [flavin-containing] B | MAO-B | MAOB | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B | Monoamine oxidase type B
Type:
PROTEIN
Mol. Mass.:
58428.94
Organism:
Bos taurus
Description:
ChEMBL_1501478
Residue:
520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWRTMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEVSALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQTGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVYYKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEERLKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTTFLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
  
Inhibitor
Name:
BDBM50073527
Synonyms:
CHEMBL3408914
Type:
Small organic molecule
Emp. Form.:
C24H19ClN4O3
Mol. Mass.:
446.886
SMILES:
Clc1ccc(cc1)C(=O)NNC(=O)Cn1c2ccccc2nc(Cc2ccccc2)c1=O
Structure:
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