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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM85826
Substrate
n/a
Ki
1400±n/a nM
Comments
PDSP_2299
Citation
 Rënyi, L; Evenden, JL; Fowler, CJ; Jerning, E; Kelder, D; Lake-Bakaar, D; Larsson, LG; Mohell, N; Sällemark, M; Ross, SB The pharmacological profile of (R)-3,4-dihydro-N-isopropyl-3-(N-isopropyl-N-propylamino)-2H-1-benzopyran-5-carboxamide, a selective 5-hydroxytryptamine(1A) receptor agonist. J Pharmacol Exp Ther 299:883-93 (2001) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | 5-hydroxytryptamine serotonin receptor 1B | HTR1B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43142.15
Organism:
BOVINE
Description:
L8IGV0
Residue:
389
Sequence:
MEAVAAQCPQPPSASSQTGLSQANLSAGPSHNCSAAEEYIYQDFIALPWKVVVVLLLALFTLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDLWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSICISLPPFFWRQAKAEAMSNCVVNTDHVLYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLAIPICTSCWFHQAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIGFKCTN
  
Inhibitor
Name:
BDBM85826
Synonyms:
(R)-N-Isopropyl-3-[isopropyl(propyl)amino]-3,4-dihydro-2H-1-benzopyran-5-carboxamide | NAE-086
Type:
Small organic molecule
Emp. Form.:
C19H30N2O2
Mol. Mass.:
318.4537
SMILES:
CCCN(C(C)C)[C@H]1COc2cccc(C(=O)NC(C)C)c2C1
Structure:
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