Compile Data Set for Download or QSAR
Report error Found 304 Enz. Inhib. hit(s) with all data for entry = 3236
TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394585BDBM394585(US10308614, Example 188 | 2-(6-amino-5-(1-(1-)
Affinity DataIC50: 2.5nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394450BDBM394450(US10308614, Example 51 | 2-(6-amino-5-(8-(5-)
Affinity DataIC50: 3.40nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394584BDBM394584(US10308614, Example 187 | 2-(6-amino-5-(1-methyl-)
Affinity DataIC50: 3.70nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394468BDBM394468(US10308614, Example 69 | 2-(6-amino-5-(8-)
Affinity DataIC50: 3.90nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394474BDBM394474(US10308614, Example 75 | 2-(6-amino-5-(8-(5-)
Affinity DataIC50: 4nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394469BDBM394469(US10308614, Example 70 | 2-(6-amino-5-(8-(pyridin-)
Affinity DataIC50: 4.10nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394462BDBM394462(US10308614, Example 63 | 2-(6-amino-5-(8-phenyl-3,...)
Affinity DataIC50: 4.30nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394446BDBM394446(US10308614, Example 47 | 2-(6-amino-5-(8-(2-)
Affinity DataIC50: 4.5nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394470BDBM394470(US10308614, Example 71 | 2-(6-amino-5-(8-)
Affinity DataIC50: 5nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394605BDBM394605(US10308614, Example 209 | 2-(6-amino-5-cyclohexylp...)
Affinity DataIC50: 5.20nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394575BDBM394575(US10308614, Example 178 | 2-(6-amino-5-(2-)
Affinity DataIC50: 5.30nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394585BDBM394585(US10308614, Example 188 | 2-(6-amino-5-(1-(1-)
Affinity DataIC50: 5.70nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvprgsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394589BDBM394589(US10308614, Example 192 | 2-(6-amino-5-(1-(1-)
Affinity DataIC50: 6.30nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394476BDBM394476(US10308614, Example 77 | 2-(6-amino-5-(8-(thiazol-)
Affinity DataIC50: 6.5nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394585BDBM394585(US10308614, Example 188 | 2-(6-amino-5-(1-(1-)
Affinity DataIC50: 6.60nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394475BDBM394475(US10308614, Example 76 | 2-(6-amino-5-(8-(4-)
Affinity DataIC50: 6.70nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394528BDBM394528(US10308614, Example 129 | 1-(4-(3-amino-6-(2-)
Affinity DataIC50: 6.80nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394575BDBM394575(US10308614, Example 178 | 2-(6-amino-5-(2-)
Affinity DataIC50: 7.20nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvprgsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394427BDBM394427(US10308614, Example 28 | US10308614, Example 84 | ...)
Affinity DataIC50: 8.40nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394605BDBM394605(US10308614, Example 209 | 2-(6-amino-5-cyclohexylp...)
Affinity DataIC50: 8.80nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvprgsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394571BDBM394571(US10308614, Example 174 | 2-(6-amino-5-)
Affinity DataIC50: 8.80nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394583BDBM394583(US10308614, Example 186 | 2-(6-amino-5-phenylpyrid...)
Affinity DataIC50: 8.90nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394567BDBM394567(US10308614, Example 170 | (S)-2-(6-amino-5-(1-)
Affinity DataIC50: 9.60nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394584BDBM394584(US10308614, Example 187 | 2-(6-amino-5-(1-methyl-)
Affinity DataIC50: 10nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvprgsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394528BDBM394528(US10308614, Example 129 | 1-(4-(3-amino-6-(2-)
Affinity DataIC50: 10.4nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394449BDBM394449(US10308614, Example 50 | 2-(6-amino-5-(8-)
Affinity DataIC50: 10.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394473BDBM394473(US10308614, Example 74 | 2-(6-amino-5-((1R,4R)-5-)
Affinity DataIC50: 10.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394485BDBM394485(US10308614, Example 85 | Enantiomer 1 and Enantiom...)
Affinity DataIC50: 11nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394441BDBM394441(US10308614, Example 42 | 1-(3-amino-6-(2-)
Affinity DataIC50: 11.3nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394461BDBM394461(US10308614, Example 62 | (4-(3-amino-6-(2-)
Affinity DataIC50: 11.7nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394595BDBM394595(US10308614, Example 198 | 2-(6-amino-5-(trans-2-ph...)
Affinity DataIC50: 12.1nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394575BDBM394575(US10308614, Example 178 | 2-(6-amino-5-(2-)
Affinity DataIC50: 12.2nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394537BDBM394537(US10308614, Example 138 | (4-(3-amino-6-(2-)
Affinity DataIC50: 12.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394584BDBM394584(US10308614, Example 187 | 2-(6-amino-5-(1-methyl-)
Affinity DataIC50: 12.8nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394456BDBM394456(US10308614, Example 57 | 2-(6-amino-5-(3-)
Affinity DataIC50: 13.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394490BDBM394490(US10308614, Example 90 | 2-(6-amino-5-(piperidin-1...)
Affinity DataIC50: 13.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394605BDBM394605(US10308614, Example 209 | 2-(6-amino-5-cyclohexylp...)
Affinity DataIC50: 14.5nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394571BDBM394571(US10308614, Example 174 | 2-(6-amino-5-)
Affinity DataIC50: 14.8nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394606BDBM394606(US10308614, Example 210 | 2-(6-amino-5-)
Affinity DataIC50: 14.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 394567BDBM394567(US10308614, Example 170 | (S)-2-(6-amino-5-(1-)
Affinity DataIC50: 14.9nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvprgsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394458BDBM394458(US10308614, Example 59 | 1-(3-amino-6-(2-)
Affinity DataIC50: 15.8nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394507BDBM394507(US10308614, Example 108 | 2-(6-amino-5-(3-methyl-4...)
Affinity DataIC50: 15.9nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394521BDBM394521(US10308614, Example 122 | 1-(4-(3-amino-6-(2-hydro...)
Affinity DataIC50: 16.3nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetProtein polybromo-1 [645-766](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394403BDBM394403(US10308614, Example 5 | 2-(6-amino-5-(4-((dimethyl...)
Affinity DataIC50: 16.4nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvprgsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSELP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394427BDBM394427(US10308614, Example 28 | US10308614, Example 84 | ...)
Affinity DataIC50: 17.2nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394580BDBM394580(US10308614, Example 183 | 2-(6-amino-5-((1-)
Affinity DataIC50: 17.2nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394424BDBM394424(US10308614, Example 25 | 2-(6-amino-5-(4-methyl-)
Affinity DataIC50: 17.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394508BDBM394508(US10308614, Example 109 | 2-(6-amino-5-(3-methyl-)
Affinity DataIC50: 17.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394587BDBM394587(US10308614, Example 190 | 2-(6-amino-5-)
Affinity DataIC50: 17.6nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

TargetTranscription activator BRG1 [1448-1575](Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 394456BDBM394456(US10308614, Example 57 | 2-(6-amino-5-(3-)
Affinity DataIC50: 17.7nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvprgsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNAQ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

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