Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 8846
TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423161(US10501438, Compound 12 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 110nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423156(US10501438, Compound 7 | 5-benzyl-6-(1,5-dimethyl-...)
Affinity DataIC50: 140nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423168(US10501438, Compound 17 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 180nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423159(US10501438, Compound 9 | 5-benzyl-6-(1,5-dimethyl-...)
Affinity DataIC50: 270nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423166(US10501438, Compound 8 | 7-benzyl-6-(1,5-dimethyl-...)
Affinity DataIC50: 280nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423154(US10501438, Compound 4)
Affinity DataIC50: 280nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423163(US10501438, Compound 14 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 350nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423160(US10501438, Compound 11 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 350nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423151(US10501438, Compound 1)
Affinity DataIC50: 410nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423164(US10501438, Compound 18 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 420nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423167(US10501438, Compound 10 | 5-benzyl-6-(1,5-dimethyl...)
Affinity DataIC50: 480nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423153(US10501438, Compound 3)
Affinity DataIC50: 510nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423152(US10501438, Compound 2)
Affinity DataIC50: 560nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423165(US10501438, Compound 19)
Affinity DataIC50: 700nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423155(US10501438, Compound 6 | 8-(cyclohexylamino)-6-(1,...)
Affinity DataIC50: 810nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Neomed Institute

US Patent
LigandPNGBDBM423162(US10501438, Compound 13 | 6-(1,5-dimethyl-6-oxo-3-...)
Affinity DataIC50: 1.30E+3nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2020
Entry Details
US Patent