Compile Data Set for Download or QSAR
Report error Found 837 Enz. Inhib. hit(s) with all data for entry = 11081
LigandChemical structure of BindingDB Monomer ID 502622BDBM502622(US11028085, Compound I-481 | US11078201, Compound ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500817BDBM500817(7-[[5-[(2R)-2-[(3- fluoroazetidin- 1-yl)methyl]mor...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500814BDBM500814((S)-7-((6- ((dimethylamino)- methyl)-5- (tetrahydr...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500820BDBM500820(7-[[5-[(2S)-2- (1-hydroxy-1- methyl-ethyl)morpholi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 588890BDBM588890(US11548890, Compound I-486)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500818BDBM500818(4-(8- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500819BDBM500819(7-[[5-[(2S)-2- (1-hydroxy-1-methyl- ethyl)morpholi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500824BDBM500824(7-[[5-[(2S)-2- (1-hydroxy-1- methylethyl)morpholin...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500825BDBM500825(7-[[5-[(2S)-2- (1-hydroxy-1- methylethyl) morpholi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500822BDBM500822(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3-yl)...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 502629BDBM502629(US11028085, Compound I-488 | US11078201, Compound ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500828BDBM500828(7-[[6- (3,3a,4,5,6,6a- hexahydro- 2]H-pyrrolo[2,3-...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500829BDBM500829(7-[[5-[(2R)-2- [[cyclopropyl (methyl)amino] methyl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500826BDBM500826(7-[[5-[3- [[cyclopropyl (methyl)amino] methyl]-3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500827BDBM500827(4-[7- (difluoromethyl)- imidazo[1,2- a]pyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500800BDBM500800(7-[[5-(4- hydroxy-1- piperidyl)-2- pyridyl]amino] ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500479BDBM500479(US11021481, Compound I-465 | 4-(7-fluoroimidazo [1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500798BDBM500798(4-(8- chloroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- 1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500799BDBM500799(4-(8-fluoro-7- methyl-imidazol [1,2- a]pyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 502610BDBM502610(US11028085, Compound I-469 | US11078201, Compound ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500802BDBM500802(4-(8-fluoro-7- methyl- imidazo[1,2- a]pyridin-3- y...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500803BDBM500803(4-(8-fluoro-7- methyl-imidazo[1,2- a]pyridin-3- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500808BDBM500808(4-(8-fluoro-7- methyl- imidazo[1,2- a]pyridin-3- y...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500809BDBM500809(7-[[5-[(2S)-2- (1-hydroxy-1- methyl-ethyl)morpholi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500806BDBM500806(7-[[5-[(2S)-2- (1-hydroxy-1- methyl-ethyl)morpholi...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500807BDBM500807(7-[[6- (3,3a,4,5,6,6a- hexahydro-2H- pyrrolo[2,3- ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500812BDBM500812(7-[[5-[(2R)-2- [(cyclopropyla mino)methyl] morphol...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500813BDBM500813((R)-7-((6- ((dimethylamino)- methyl)-5- (tetrahydr...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 502616BDBM502616(US11028085, Compound I-475 | US11078201, Compound ...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500811BDBM500811(Formic acid salt 4-(7-fluoroimidazo [1,2-a]pyridin...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500848BDBM500848(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5- [...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500849BDBM500849(4-(7- f1uoroimidazo [1,2-a]pyridin- 3-yl)-7-((5- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500846BDBM500846((R)-7-((6- ((diethylamino)- methyl)-5- (tetrahydro...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500847BDBM500847((S)-7-((6- ((diethylamino) methyl)-5- (tetrahydrof...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500852BDBM500852((S)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500853BDBM500853(7-[ [5-[3- [(dimethylamino)- methyl]mor- pholin-4-...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500850BDBM500850(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((5- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500851BDBM500851((R)-4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500856BDBM500856(US11021481, Compound I-520 | (S)-7-((5-(1- (dimeth...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500856BDBM500856(US11021481, Compound I-520 | (S)-7-((5-(1- (dimeth...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500854BDBM500854((S)-7-((5-(6- (dimethylami- no)-1,4-oxazepan-4- yl...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500855BDBM500855((R)-7-((5-(6- (dimethylami- no)-1,4- oxazepan-4- y...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500860BDBM500860(7-[[6- [(dimethylamino)- methyl]-5-[(3R)-3- hydrox...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500861BDBM500861(7-[[6- [(dimethylamino)- methyl]-5-(7-oxa-4- azasp...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500858BDBM500858(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((5- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500859BDBM500859(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((5- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500832BDBM500832(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500833BDBM500833(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-((6- (...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500830BDBM500830(7-[[5-[(2S)-2- [(cyclopropyl- amino)methyl] morpho...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 500831BDBM500831(4-(7- fluoroimidazo [1,2-a]pyridin- 3-yl)-7-[[5-(4...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

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