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Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 11421
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM613985((3S,4S)-8-{7-[(2-amino-3-chloropyridin-4-yl)sulfan...)
Affinity DataIC50:  34nMAssay Description:The phosphatase reactions were performed at room temperature in 96-well black polystyrene plate, flat bottom, non-binding surface (Corning, Cat #3650...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM613988((3S,4S)-8-{8-[(2-amino-3-chloropyridin-4-yl)sulfan...)
Affinity DataIC50:  83nMAssay Description:The phosphatase reactions were performed at room temperature in 96-well black polystyrene plate, flat bottom, non-binding surface (Corning, Cat #3650...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM50546224(CHEMBL4746963 | US11739093, Compound 2 | US2024019...)
Affinity DataIC50:  190nMAssay Description:The phosphatase reactions were performed at room temperature in 96-well black polystyrene plate, flat bottom, non-binding surface (Corning, Cat #3650...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM613987(4-((4-(4-amino-4-methylpiperidin-1-yl)-[1,2,5]thia...)
Affinity DataIC50:  340nMAssay Description:The phosphatase reactions were performed at room temperature in 96-well black polystyrene plate, flat bottom, non-binding surface (Corning, Cat #3650...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM613986((3S,4S)-8-{5-[(2-amino-3-chloropyridin-4-yl)sulfan...)
Affinity DataIC50:  1.10E+3nMAssay Description:The phosphatase reactions were performed at room temperature in 96-well black polystyrene plate, flat bottom, non-binding surface (Corning, Cat #3650...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent