Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 11425
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614208(US11746110, Example 3)
Affinity DataIC50: 0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614207(US11746110, Example 2)
Affinity DataIC50: 0.320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614220(US11746110, Example 15)
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614219(US11746110, Example 14)
Affinity DataIC50: 0.490nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614155(US11746110, Example 1)
Affinity DataIC50: 0.880nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614214(US11746110, Example 9)
Affinity DataIC50: 0.930nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614220(US11746110, Example 15)
Affinity DataIC50: 1.42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614211(US11746110, Example 6)
Affinity DataIC50: 1.60nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614208(US11746110, Example 3)
Affinity DataIC50: 1.89nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614217(US11746110, Example 12)
Affinity DataIC50: 2.24nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614213(US11746110, Example 8)
Affinity DataIC50: 2.55nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614207(US11746110, Example 2)
Affinity DataIC50: 2.69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614215(US11746110, Example 10)
Affinity DataIC50: 2.70nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614220(US11746110, Example 15)
Affinity DataIC50: 3.24nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614210(US11746110, Example 5)
Affinity DataIC50: 3.33nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614210(US11746110, Example 5)
Affinity DataIC50: 3.44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614155(US11746110, Example 1)
Affinity DataIC50: 3.91nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614216(US11746110, Example 11)
Affinity DataIC50: 4.18nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614220(US11746110, Example 15)
Affinity DataIC50: 4.28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614219(US11746110, Example 14)
Affinity DataIC50: 4.91nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614209(US11746110, Example 4)
Affinity DataIC50: 4.93nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614213(US11746110, Example 8)
Affinity DataIC50: 6.47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614207(US11746110, Example 2)
Affinity DataIC50: 6.65nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614209(US11746110, Example 4)
Affinity DataIC50: 7.69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614155(US11746110, Example 1)
Affinity DataIC50: 9.05nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614218(US11746110, Example 13)
Affinity DataIC50: 9.88nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614219(US11746110, Example 14)
Affinity DataIC50: 9.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614207(US11746110, Example 2)
Affinity DataIC50: 10.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614155(US11746110, Example 1)
Affinity DataIC50: 12.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614219(US11746110, Example 14)
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614214(US11746110, Example 9)
Affinity DataIC50: 19.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614208(US11746110, Example 3)
Affinity DataIC50: 23.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614208(US11746110, Example 3)
Affinity DataIC50: 27.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614212(US11746110, Example 7)
Affinity DataIC50: 32.1nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614216(US11746110, Example 11)
Affinity DataIC50: 57.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614211(US11746110, Example 6)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1 [T315I](Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614218(US11746110, Example 13)
Affinity DataIC50: 67.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614221(US11746110, Example 16)
Affinity DataIC50: 82.9nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent