Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 11975
LigandPNGBDBM50469331(CHEMBL4282980 | US11958846, Example 6)
Affinity DataIC50: 5nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469320(CHEMBL4293567 | US11958846, Example 5)
Affinity DataIC50: 5nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469330(CHEMBL4295096 | US11958846, Example 7)
Affinity DataIC50: 5nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469331(CHEMBL4282980 | US11958846, Example 6)
Affinity DataIC50: 5nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469324(CHEMBL4286345 | US11958846, Example 4)
Affinity DataIC50: 5nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469320(CHEMBL4293567 | US11958846, Example 5)
Affinity DataIC50: 5nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469324(CHEMBL4286345 | US11958846, Example 4)
Affinity DataIC50: 5nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469330(CHEMBL4295096 | US11958846, Example 7)
Affinity DataIC50: 5nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469329(CHEMBL4278436 | US11958846, Example 1)
Affinity DataIC50: 5nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469329(CHEMBL4278436 | US11958846, Example 1)
Affinity DataIC50: 6nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469325(CHEMBL4294655 | US11958846, Example 3)
Affinity DataIC50: 10nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469325(CHEMBL4294655 | US11958846, Example 3)
Affinity DataIC50: 10nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM667812(US11958846, Example 8 | 1-(3-(difluoromethyl)isoth...)
Affinity DataIC50: 19nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

TargetTranscription activator BRG1 [658-1361](Human)
Novartis

US Patent
LigandPNGBDBM50469321(CHEMBL4286757 | US11958846, Example 2)
Affinity DataIC50: 30nMAssay Description:Compound inhibition of ATPase activity of Brm ATPase-SnAC (636-1331) was measured by using the ADP-Glo assay kit from Promega (V6930). 120 nL of comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM50469321(CHEMBL4286757 | US11958846, Example 2)
Affinity DataIC50: 33nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

LigandPNGBDBM667812(US11958846, Example 8 | 1-(3-(difluoromethyl)isoth...)
Affinity DataIC50: 90nMAssay Description:All subsequent reagent additions were performed using a MultiFlo FX Multi-Mode Dispenser. Assay buffer was 20 mM HEPES pH 7.5, 1 mM MgCl2, 20 mM KCl,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent