Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12042
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674436BDBM674436(US20240150370, Example 25)
Affinity DataIC50: 5.80E+3nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674435BDBM674435(US20240150370, Example 24)
Affinity DataIC50: 6.90E+3nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674431BDBM674431(US20240150370, Example 16)
Affinity DataIC50: 6.86E+4nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674459BDBM674459(rac-1-(5′-methyl-3′H-spiro[cyclopropan...)
Affinity DataIC50: 7.18E+4nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674458BDBM674458(rac-1-(2-methoxy-5,6,7,8-tetrahydroquinolin-8-yl)m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674460BDBM674460(rel-1-[(3'S)-3′H-spiro[cyclopropane-1,2̸...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674447BDBM674447(rac-1-(3,4-dihydro-2H-thiopyrano[3,2-b]pyridin-4-y...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674446BDBM674446(rel-1-[(2S,3R)-2-ethyl-2,3-dihydrofuro[3,2-b]pyrid...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674449BDBM674449(US20240150370, Example 47)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674448BDBM674448(N-methyl-1-[(2R,3S)-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674443BDBM674443(rel-1-[(4S)-3,4-dihydro-2H-thiopyrano[3,2-b]pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674442BDBM674442(1-[(2R,3S)-5-chloro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674445BDBM674445(rel-1-[(3S)-2,3-dihydrothieno[3,2-b]pyridin-3-yl]m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674444BDBM674444(rel-1-[(3R)-2,3-dihydrothieno[3,2-b]pyridin-3-yl]m...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674455BDBM674455(US20240150370, Example 79)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674454BDBM674454(US20240150370, Example 58)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674457BDBM674457(US20240150370, Example 84)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674456BDBM674456(US20240150370, Example 83)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674451BDBM674451(1-[(2R,3S)-6-fluoro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674450BDBM674450(US20240150370, Example 48)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674453BDBM674453(US20240150370, Example 51)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674452BDBM674452(US20240150370, Example 50)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674430BDBM674430(US20240150370, Example 15)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674433BDBM674433(US20240150370, Example 22)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674432BDBM674432(US20240150370, Example 18)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674427BDBM674427(US20240150370, Example 11)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674426BDBM674426(US20240150370, Example 9)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674429BDBM674429(US20240150370, Example 14)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674428BDBM674428(US20240150370, Example 12)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674439BDBM674439(1-[(2R,3S)-2,7-dimethyl-2,3-dihydrofuro[3,2-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674438BDBM674438(US20240150370, Example 29)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674441BDBM674441(1-[(2R,3S)-6-chloro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674440BDBM674440(1-[(2R,3S)-2,5-dimethyl-2,3-dihydrofuro[3,2-b]pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674434BDBM674434(US20240150370, Example 23)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674437BDBM674437(1-[(2R,3S)-2-methyl-2,3-dihydrofuro[3,2-b]pyridin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674423BDBM674423(US20240150370, Example 6)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674422BDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674425BDBM674425(1-[(2R,3S)-6-fluoro-2-methyl-2,3-dihydrofuro[3,2-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674422BDBM674422(N-methyl-1-[(2R,4S)-2-methyl-3,4-dihydro-2H-pyrano...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 674421BDBM674421(rac-1-[(3S,4S)-3-methyl-3,4-dihydro-2H-pyrano[3,2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The hERG channel inhibitory effect of the disclosed compounds was measured by a whole-cell patch clamp method using an autopatch clamp system using C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent