Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 6663
TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144347BDBM144347(US8969348, {4-[(1,4-Dimethyl-1H-indol-3-yl)methyl]...)
Affinity DataIC50: 7nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144346BDBM144346(US8969348, 2-{4-[(1,4-Dimethyl-1H-indol-3-yl)methy...)
Affinity DataIC50: 9nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144340BDBM144340(US8969348, {4-[(1,4-Dimethyl-1H-indol-3-yl)methyl]...)
Affinity DataIC50: 50nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144344BDBM144344(US8969348, 2-[4-(Naphthalen-1-ylmethyl)-1-oxophtha...)
Affinity DataIC50: 86nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144348BDBM144348(US8969348, 2-{4-[(1-Methyl-1H-indol-3-yl)methyl]-1...)
Affinity DataIC50: 93nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144341BDBM144341(US8969348, [4-(Naphthalen-1-ylmethyl)-1-oxophthala...)
Affinity DataIC50: 150nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144342BDBM144342(US8969348, 3-{4-[(1,4-Dimethyl-1H-indol-3-yl)methy...)
Affinity DataIC50: 160nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144343BDBM144343(US8969348, [4-(Naphthalen-1-ylmethyl)-1-oxophthala...)
Affinity DataIC50: 170nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144339BDBM144339(US8969348, {4-[(1-Methyl-1H-indol-3-yl)methyl]-1-o...)
Affinity DataIC50: 300nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetChymase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 144345BDBM144345(US8969348, {4-[(1-Methyl-1H-indol-3-yl)methyl]-1-o...)
Affinity DataIC50: 360nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent