Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 6998
TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164488BDBM164488(US9066954, 373)
Affinity DataKi:  0.100nM ΔG°:  -57.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164473BDBM164473(US9066954, 302)
Affinity DataKi:  0.300nM ΔG°:  -54.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164486BDBM164486(US9066954, 336)
Affinity DataKi:  0.700nM ΔG°:  -52.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164420BDBM164420(US9066954, 55)
Affinity DataKi:  0.900nM ΔG°:  -52.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164453BDBM164453(US9066954, 176)
Affinity DataKi:  1.20nM ΔG°:  -51.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 24483BDBM24483(5-(3-{[(7-methoxyquinolin-4-yl)oxy]methyl}-[1,2,4]...)
Affinity DataKi:  1.60nM ΔG°:  -50.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164424BDBM164424(US9066954, 62)
Affinity DataKi:  1.70nM ΔG°:  -50.4kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164434BDBM164434(US9066954, 85)
Affinity DataKi:  2nM ΔG°:  -50.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164475BDBM164475(US9066954, 309)
Affinity DataKi:  2nM ΔG°:  -50.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164430BDBM164430(US9066954, 75)
Affinity DataKi:  2.20nM ΔG°:  -49.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164435BDBM164435(US9066954, 86)
Affinity DataKi:  2.40nM ΔG°:  -49.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164457BDBM164457(US9066954, 202)
Affinity DataKi:  2.40nM ΔG°:  -49.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164441BDBM164441(US9066954, 118)
Affinity DataKi:  2.60nM ΔG°:  -49.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164464BDBM164464(US9066954, 232)
Affinity DataKi:  2.60nM ΔG°:  -49.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50302903BDBM50302903(7-methoxy-N-((6-(3,4,5-trifluorophenyl)-[1,2,4]tri...)
Affinity DataKi:  2.70nM ΔG°:  -49.2kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164469BDBM164469(US9066954, 294)
Affinity DataKi:  2.80nM ΔG°:  -49.1kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164446BDBM164446(US9066954, 141)
Affinity DataKi:  2.90nM ΔG°:  -49.1kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50302905BDBM50302905(7-methoxy-N-((6-(3-methylisothiazol-5-yl)-[1,2,4]t...)
Affinity DataKi:  3.20nM ΔG°:  -48.8kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164472BDBM164472(US9066954, 297)
Affinity DataKi:  3.20nM ΔG°:  -48.8kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164461BDBM164461(US9066954, 226)
Affinity DataKi:  4.70nM ΔG°:  -47.9kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164455BDBM164455(US9066954, 187)
Affinity DataKi:  4.90nM ΔG°:  -47.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164418BDBM164418(US9066954, 52)
Affinity DataKi:  5nM ΔG°:  -47.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164445BDBM164445(US9066954, 140)
Affinity DataKi:  5.20nM ΔG°:  -47.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164442BDBM164442(US9066954, 121)
Affinity DataKi:  5.40nM ΔG°:  -47.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164454BDBM164454(US9066954, 186)
Affinity DataKi:  6.20nM ΔG°:  -47.2kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164404BDBM164404(US9066954, 18)
Affinity DataKi:  6.60nM ΔG°:  -47.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164419BDBM164419(US9066954, 53)
Affinity DataKi:  6.70nM ΔG°:  -47.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164463BDBM164463(US9066954, 231)
Affinity DataKi:  6.70nM ΔG°:  -47.0kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164476BDBM164476(US9066954, 311)
Affinity DataKi:  7nM ΔG°:  -46.9kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 24472BDBM24472(4-{[6-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyrid...)
Affinity DataKi:  7nM ΔG°:  -46.9kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164458BDBM164458(US9066954, 203)
Affinity DataKi:  7.5nM ΔG°:  -46.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164414BDBM164414(US9066954, 40)
Affinity DataKi:  7.5nM ΔG°:  -46.7kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164438BDBM164438(US9066954, 89)
Affinity DataKi:  7.90nM ΔG°:  -46.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164460BDBM164460(US9066954, 209)
Affinity DataKi:  8.90nM ΔG°:  -46.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164471BDBM164471(US9066954, 296)
Affinity DataKi:  8.90nM ΔG°:  -46.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 50440890BDBM50440890(CHEMBL2431841 | US9066954, 341)
Affinity DataKi:  9.10nM ΔG°:  -46.2kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164448BDBM164448(US9066954, 148)
Affinity DataKi:  9.20nM ΔG°:  -46.2kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164403BDBM164403(US9066954, 17)
Affinity DataKi:  9.30nM ΔG°:  -46.1kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164467BDBM164467(US9066954, 282)
Affinity DataKi:  9.5nM ΔG°:  -46.1kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164493BDBM164493(US9066954, 447)
Affinity DataKi:  12.1nM ΔG°:  -45.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164416BDBM164416(US9066954, 45)
Affinity DataKi:  12.1nM ΔG°:  -45.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164429BDBM164429(US9066954, 73)
Affinity DataKi:  12.8nM ΔG°:  -45.4kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164411BDBM164411(US9066954, 34)
Affinity DataKi:  15.9nM ΔG°:  -44.8kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164409BDBM164409(US9066954, 24)
Affinity DataKi:  17.4nM ΔG°:  -44.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 24484BDBM24484(4-{[6-(furan-2-yl)-[1,2,4]triazolo[4,3-a]pyridazin...)
Affinity DataKi:  17.6nM ΔG°:  -44.6kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164439BDBM164439(US9066954, 91)
Affinity DataKi:  19.2nM ΔG°:  -44.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164465BDBM164465(US9066954, 279)
Affinity DataKi:  19.7nM ΔG°:  -44.3kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164428BDBM164428(US9066954, 70)
Affinity DataKi:  22.9nM ΔG°:  -43.9kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164459BDBM164459(US9066954, 208)
Affinity DataKi:  23.7nM ΔG°:  -43.8kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 164417BDBM164417(US9066954, 50)
Affinity DataKi:  23.8nM ΔG°:  -43.8kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

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