Compile Data Set for Download or QSAR
Report error Found 152 Enz. Inhib. hit(s) with all data for entry = 8115
TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233415BDBM233415(US9351965, 22)
Affinity DataIC50: 2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233416BDBM233416(US9351965, 23)
Affinity DataIC50: 2.20nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233459BDBM233459(US9351965, 66)
Affinity DataIC50: 7nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233394BDBM233394(US9351965, 3 | US9351965, 2 | US9351965, 4 | US935...)
Affinity DataIC50: 7.60nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233472BDBM233472(US9351965, 79)
Affinity DataIC50: 8.60nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233408BDBM233408(US9351965, 15)
Affinity DataIC50: 8.60nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233417BDBM233417(US9351965, 24)
Affinity DataIC50: 8.90nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233516BDBM233516(US9351965, 123)
Affinity DataIC50: 10.7nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233485BDBM233485(US9351965, 92)
Affinity DataIC50: 10.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233435BDBM233435(US9351965, 42)
Affinity DataIC50: 11.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233412BDBM233412(US9351965, 19)
Affinity DataIC50: 12.1nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233436BDBM233436(US9351965, 45 | US9351965, 44 | US9351965, 43)
Affinity DataIC50: 13.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233515BDBM233515(US9351965, 122)
Affinity DataIC50: 14.3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233405BDBM233405(US9351965, 12)
Affinity DataIC50: 14.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233398BDBM233398(US9351965, 8 | US9351965, 7 | US9351965, 6 | US935...)
Affinity DataIC50: 15.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233507BDBM233507(US9351965, 114)
Affinity DataIC50: 15.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233407BDBM233407(US9351965, 14)
Affinity DataIC50: 15.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233513BDBM233513(US9351965, 120)
Affinity DataIC50: 17.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233531BDBM233531(US9351965, 139 | US9351965, 138)
Affinity DataIC50: 19.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233454BDBM233454(US9351965, 61)
Affinity DataIC50: 19.3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233455BDBM233455(US9351965, 62)
Affinity DataIC50: 19.9nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233406BDBM233406(US9351965, 13)
Affinity DataIC50: 19.9nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233394BDBM233394(US9351965, 3 | US9351965, 2 | US9351965, 4 | US935...)
Affinity DataIC50: 20.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233414BDBM233414(US9351965, 21)
Affinity DataIC50: 20.9nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233502BDBM233502(US9351965, 109)
Affinity DataIC50: 21.1nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233496BDBM233496(US9351965, 103)
Affinity DataIC50: 21.3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233442BDBM233442(US9351965, 50 | US9351965, 52 | US9351965, 51 | US...)
Affinity DataIC50: 25nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233535BDBM233535(US9351965, 143 | US9351965, 142)
Affinity DataIC50: 26.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233483BDBM233483(US9351965, 90)
Affinity DataIC50: 27.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233432BDBM233432(US9351965, 40 | US9351965, 39)
Affinity DataIC50: 28.5nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233538BDBM233538(US9351965, 145)
Affinity DataIC50: 28.7nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233501BDBM233501(US9351965, 108)
Affinity DataIC50: 29.3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233429BDBM233429(US9351965, 140 | US9351965, 141 | US9351965, 36)
Affinity DataIC50: 31.3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233543BDBM233543(US9351965, 150)
Affinity DataIC50: 32.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233508BDBM233508(US9351965, 115)
Affinity DataIC50: 33.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233413BDBM233413(US9351965, 20)
Affinity DataIC50: 33.9nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233487BDBM233487(US9351965, 94)
Affinity DataIC50: 35nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233473BDBM233473(US9351965, 80)
Affinity DataIC50: 35.1nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233514BDBM233514(US9351965, 121)
Affinity DataIC50: 37.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233450BDBM233450(US9351965, 57)
Affinity DataIC50: 37.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233422BDBM233422(US9351965, 30 | BDBM233428 | US9351965, 34 | US935...)
Affinity DataIC50: 38.6nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233429BDBM233429(US9351965, 140 | US9351965, 141 | US9351965, 36)
Affinity DataIC50: 40.4nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233410BDBM233410(US9351965, 17)
Affinity DataIC50: 44.9nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233442BDBM233442(US9351965, 50 | US9351965, 52 | US9351965, 51 | US...)
Affinity DataIC50: 47.5nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233402BDBM233402(US9351965, 9)
Affinity DataIC50: 48.7nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233462BDBM233462(US9351965, 69)
Affinity DataIC50: 53nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233519BDBM233519(US9351965, 126)
Affinity DataIC50: 56.6nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233511BDBM233511(US9351965, 118)
Affinity DataIC50: 60.8nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233420BDBM233420(US9351965, 33 | US9351965, 28 | US9351965, 27)
Affinity DataIC50: 61nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 233451BDBM233451(US9351965, 58)
Affinity DataIC50: 62nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

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