Found 177 with Last Name = 'jacobsen' and Initial = 'h' 
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0370nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human BACE2 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human BACE1 in HEK293 cells transfected with wild type APP assessed as reduction of amyloid beta40 level after 18 to 20 hrs by AlphaLIS...More data for this Ligand-Target Pair
