BDBM102450 US8536165, 8

SMILES Cc1ccc(Nc2cnc(c(F)c2)-c2ccccc2)c(c1)C(O)=O

InChI Key InChIKey=PFGOXABJGOKVCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102450   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM102450(US8536165, 8)
Affinity DataIC50:  18nMpH: 8.0Assay Description:Inhibition of human DHODH activity assay: DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichloroph...More data for this Ligand-Target Pair
In DepthDetails US Patent