BDBM10317 (2S)-1-[(2,3-dioxo-2,3-dihydro-1H-indole-5-)sulfonyl]-N-phenylpyrrolidine-2-carboxamide::(S)-5-{1-[2-(Phenylaminocarbonyl)pyrrolidinyl]sulfonyl}-isatin::Isatin Sulfonamide 28

SMILES O=C(Nc1ccccc1)[C@@H]1CCCN1S(=O)(=O)c1ccc2NC(=O)C(=O)c2c1

InChI Key InChIKey=VQLGPFBCZJQNDY-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10317   

TargetCaspase-3(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM10317((2S)-1-[(2,3-dioxo-2,3-dihydro-1H-indole-5-)sulfon...)
Affinity DataIC50:  140nMAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed