BDBM120095 US10525036, Example GDC-0994::US10934304, Example GDC-0994::US8697715, 39::US9259470, 39

SMILES Cn1nccc1Nc1nccc(n1)-c1ccn([C@H](CO)c2ccc(Cl)c(F)c2)c(=O)c1

InChI Key InChIKey=RZUOCXOYPYGSKL-GOSISDBHSA-N

Data  17 IC50  5 Kd

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120095   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM120095(US10525036, Example GDC-0994 | US10934304, Example...)
Affinity DataIC50:  3.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair