BDBM14824 4-({5-bromo-4-[(4-methoxyphenyl)amino]pyrimidin-2-yl}amino)benzoic acid::AstraZeneca compound 1::JMC514672 Compound 30
SMILES COc1ccc(Nc2nc(Nc3ccc(cc3)C(O)=O)ncc2Br)cc1
InChI Key InChIKey=YMPWYIHAVYUJEK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 14824
Affinity DataIC50: 646nMpH: 7.4 T: 2°CAssay Description:TrkB kinase activity was measured against its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using homog...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMpH: 7.5 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified recombinant Chk1 and biotinylated peptide substrate in the presence ATP/[...More data for this Ligand-Target Pair