BDBM20725 (1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}phenyl)phenyl]carbonyl}cyclopentane-1-carboxylic acid::Urea-based Analogue, 4i

SMILES OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccc(cc2)C#N)cc1

InChI Key InChIKey=FIXXEIAIMXXMQZ-DNQXCXABSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20725   

TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Abbott Laboratories

LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50:  603nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50:  35nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed