BDBM212579 US10155731, Example 270::US9278944, 270

SMILES COC(=O)NCCCn1nc([C@@H](C)N(C2CC2)C(=O)[C@H]2CNCCO2)c2ccc(C)nc12

InChI Key InChIKey=GRTDDIZIUSADLD-CRAIPNDOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212579   

TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.450nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In DepthDetails PubMed