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Found 4 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM212579'
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.400nMAssay Description:A substrate of synthetic peptide (Nma-KHPFHLVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotome...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.400nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluores...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM212579(US10155731, Example 270 | US9278944, 270)
Affinity DataIC50:  0.450nMAssay Description:Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed