BDBM238895 US10053433, Casodex (CDX)::US10053433, FC 4.037 (N- CDX)

SMILES C[C@](O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1cnc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=JWQMHMGGGRQTSY-INIZCTEOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 238895   

TargetAndrogen receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, Casodex (CDX) | US10053433, FC 4.037 (...)
Affinity DataIC50:  360nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, Casodex (CDX) | US10053433, FC 4.037 (...)
Affinity DataIC50:  190nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, Casodex (CDX) | US10053433, FC 4.037 (...)
Affinity DataIC50:  15nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAndrogen receptor(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM238895(US10053433, Casodex (CDX) | US10053433, FC 4.037 (...)
Affinity DataIC50:  1.00E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent