BDBM24709 6,9-Diamino-2-Ethoxyacridine::7-ethoxyacridine-3,9-diamine::CHEMBL94007
SMILES CCOc1ccc2nc3cc(N)ccc3c(N)c2c1
InChI Key InChIKey=CIKWKGFPFXJVGW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 24709
Affinity DataKi: 490nM ΔG°: -8.52kcal/molepH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: 1.71E+4nM ΔG°: -6.43kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-5.40kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition constants were calculated by assessment of the reduction in the formation of o-nitrophenol, as monitored by a spectrophotometric assay at ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.35E+4nMAssay Description:Inhibition of [3H]N-propylnorapomorphine binding to Dopamine receptor D2 of rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)More data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from underivatized resinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity of the compound against telomerase (Compound released from underivatized resinMore data for this Ligand-Target Pair