BDBM25375 (R)-(hydroxyethylamino)sulfonamide isostere, 3l::4,4-dioxo-1,7,4-dioxathiecan-9-yl N-[(2S,3R)-3-hydroxy-4-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]-1-phenylbutan-2-yl]carbamate::US8501961, 26::US8501961, 3l

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC1COCCS(=O)(=O)CCOC1

InChI Key InChIKey=RSIZVCJHRDDDBO-WUFINQPMSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25375   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Purdue Research Foundation

US Patent
LigandPNGBDBM25375((R)-(hydroxyethylamino)sulfonamide isostere, 3l | ...)
Affinity DataKi:  1.90nMAssay Description:Enzyme inhibitory assay utilizes a protocol described by Toth and Marshall (Toth, M. V.; Marshall G.R. A simple, continuous fluormetric assay for HIV...More data for this Ligand-Target Pair
In DepthDetails US Patent