BDBM260464 US10428074, Example 23::US9527851, 23

SMILES CN([C@H]1C[C@H]2CN(C[C@H]2C1)C(=O)CO)c1ncnc2[nH]ccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260464   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM260464(US10428074, Example 23 | US9527851, 23)
Affinity DataIC50:  21nMpH: 7.3 T: 2°CAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The test ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent