BDBM262687 3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4-yl)ethyl)-2-(2H- tetrazol-5-yl)benzenesulfonamide::US9708336, 540

SMILES Nc1nc2c(cccc2s1)-c1ccc(CCC2CCNCC2)c(c1-c1nn[nH]n1)S(N)(=O)=O

InChI Key InChIKey=AJTQAFXTVVRQHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262687   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262687(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...)
Affinity DataIC50:  20.8nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262687(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...)
Affinity DataIC50:  6.70nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262687(3-(2-Aminobenzo[d]thiazol-4-yl)-6- (2-(piperidin-4...)
Affinity DataIC50:  0.199nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent