BDBM287809 1-[4-(5,11-dihydro-6H- pyrido[2,3-b] [1,5]benzodiazepin-6- ylcarbonyl)bicyclo[2.2.2] oct-2-en-1-yl]ethanone::US10086000, Example 27::US10508108, Example 27
SMILES CC(=O)C12CCC(CC1)(C=C2)C(=O)N1Cc2cccnc2Nc2ccccc12
InChI Key InChIKey=KZMUGPYUDXHKHK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 287809
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.44E+3nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series. 125 nL of each dilution or DMSO alone is disp...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 1.44E+3nMpH: 7.0 T: 2°CAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series. 125 nL of each dilution or DMSO alone is disp...More data for this Ligand-Target Pair