BDBM291165 2-(4-Fluoro-N-isopropylphenylsulfonamido)-N-((6-(4-(trifluoromethyl)piperidin-1-yl)pyrimidin-4-yl)methyl)acetamide::US9580411, Example 80

SMILES CC(C)N(CC(=O)NCc1cc(ncn1)N1CCC(CC1)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=IQOCOSWVNOLOJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291165   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM291165(2-(4-Fluoro-N-isopropylphenylsulfonamido)-N-((6-(4...)
Affinity DataIC50:  251nMT: 2°CAssay Description:IC50s (effective concentration) of compounds on the human TRPA1 channel were determined using a Hamamatsu FDSS fluorescence plate reader. CHO cells e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent