BDBM311398 US10155763, Example 6

SMILES Cc1cccc(n1)-c1nc2NCCn2c1-c1cc2cnccc2s1

InChI Key InChIKey=FPKHCAHBTFJUMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 311398   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM311398(US10155763, Example 6)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM311398(US10155763, Example 6)
Affinity DataIC50:  6.10nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent