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Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM311398'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM311398(US10155763, Example 6)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Yanbian University

Curated by ChEMBL
LigandPNGBDBM311398(US10155763, Example 6)
Affinity DataIC50:  6.10nMAssay Description:The kinase activity of ALK5 was assessed by measuring radiolabelled phosphate[33P] incorporation into the generic substrate, casein. The kinase domai...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent