BDBM312714 1-[4-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin-3- yl]ethynyl]-2-pyridyl]-6,6- dimethyl-5,7-dihydro-4H-inda- zole-3-carboxamide::US9605005, Example 4
SMILES CN1CC[C@@](O)(C#Cc2ccnc(c2)-n2nc(C(N)=O)c3CCC(C)(C)Cc23)C1=O
InChI Key InChIKey=FCZJJTJMGRMWGH-QFIPXVFZSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312714
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 2.92nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair