BDBM318143 US10301317, Example 99::US9624228, Example 99

SMILES COc1ncc(cn1)-c1n[nH]c2cc3NC(=O)N(Cc4ccc(F)cc4F)Cc3cc12

InChI Key InChIKey=PWDBXQWLKSOPKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318143   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318143(US10301317, Example 99 | US9624228, Example 99)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Kura Oncology

US Patent
LigandPNGBDBM318143(US10301317, Example 99 | US9624228, Example 99)
Affinity DataIC50: <50nMAssay Description:The inhibition of ERK activity by the compounds disclosed herein was determined using the Z′-LYTE kinase assay kit (Life Technologies) with a S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent