BDBM348706 4-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-3-yl]phenyl]-3-propyl-1H-pyrazole-5-carboxamide::US9790230, Example 68

SMILES CCCC(=N)C(\Cl)=C(/N)C(=O)Nc1ccc(cc1)[C@@H]1O[C@H]2CN[C@@H]1C2

InChI Key InChIKey=XQRZSPCIELIJGF-HDWMDYSKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 348706   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM348706(4-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50:  17.9nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM348706(4-Chloro-N-[4-[(1R,3S,4R)-2-oxa-5-azabicyclo[2.2.1...)
Affinity DataIC50:  3.10nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent