BDBM35055 N-acylpolyamine (NAPA) scaffold, 2

SMILES CC(C)CCCNC(=O)N(CC(CCC(O)=O)NC(N)=O)C(CCCCN)CN(C(CCC(O)=O)CN(CCC(N)=O)C(=O)NCCc1ccccc1)C(=O)NCCc1ccc(Cl)cc1

InChI Key InChIKey=DJPWZVMYMCRHRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35055   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Nih

LigandPNGBDBM35055(N-acylpolyamine (NAPA) scaffold, 2)
Affinity DataIC50:  8.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibitory activities of NAPAs were measured by fluorescence anisotropy competition experiments. Protein was incubated with fluorescein-labeled huma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed