BDBM357653 3-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin- 7- yl)methyl) benzonitrile::US10214527, Example 25

SMILES Nc1cc(Cc2cccc(c2)C#N)c2nn[nH]c2n1

InChI Key InChIKey=WUXAUJNGHXFEJP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357653   

TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357653(3-((5-amino- 3H- [1,2,3]triazolo [4,5-b] pyridin- ...)
Affinity DataIC50:  55nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent