BDBM385240 US10287267, Compound 707::US10508099, Compound 707::US10556885, Compound 707::US11174244, Compound 707::US11673881, Compound 707

SMILES CN(C)[C@H]1CC[C@@H](CC1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncs1

InChI Key InChIKey=ZBGCIWMQRDNQCF-PPUGGXLSSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 385240   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385240(US10287267, Compound 707 | US10508099, Compound 70...)
Affinity DataEC50:  0.900nMAssay Description:The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions. This is a non-radioactive...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM385240(US10287267, Compound 707 | US10508099, Compound 70...)
Affinity DataEC50:  46nMAssay Description:GSK3B: This is a non-radioactive assay using fluorescence resonance energy transfer (FRET) between coumarin and fluorescein to detect kinase activity...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent