BDBM395371 US10308636, Example 57

SMILES COC[C@@]1(CC[C@@H](CC1)Oc1ccc(cn1)-c1ccc(cc1)-c1nnc([nH]1)C(F)(F)F)C(O)=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395371   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395371(US10308636, Example 57)
Affinity DataIC50:  76nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent