BDBM420316 2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-[(1-methylethyl)oxy]benzamide::US10478426, Example 24
SMILES CC(C)Oc1cc(Cl)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1Cl
InChI Key InChIKey=BQIRDGDOTJKBAB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 420316
TargetHistone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2(Homo sapiens (Human))
Glaxosmithkline
US Patent
Glaxosmithkline
US Patent
Affinity DataIC50: 250nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info