BDBM420316 2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-[(1-methylethyl)oxy]benzamide::US10478426, Example 24

SMILES CC(C)Oc1cc(Cl)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1Cl

InChI Key InChIKey=BQIRDGDOTJKBAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420316   

LigandPNGBDBM420316(2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-...)
Affinity DataIC50:  250nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent