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Found 1 Enz. Inhib. hit(s) with Target = 'Histone-binding protein RBBP4/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2' and Ligand = 'BDBM420316'
LigandPNGBDBM420316(2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-...)
Affinity DataIC50:  250nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent