BDBM430630 US10550096, Example 3

SMILES CCc1nn(C[C@@H](O)[C@@H]2Cc3ccccc3CN2)c(=O)c2ccc(cc12)C(=O)N1C2CCC1COC2

InChI Key InChIKey=SQAZZNZMYHUBFP-FTZAUHMMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 430630   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM430630(US10550096, Example 3)
Affinity DataIC50:  1nMAssay Description:The cell line TE11 was seeded at a density of 6,000 cells per well in 96 well optical quality tissue culture plates in DME medium and 10% foetal bovi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM430630(US10550096, Example 3)
Affinity DataIC50:  39nMAssay Description:A histone H4 derived peptide is used as substrate (amino acid sequence: Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-L...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent