BDBM435324 N-((2-(2-(((trans)-2- (methoxymethyl)cyclopentyl)amino)-2- oxoethyl)-5-(3-(trifluoromethoxy)phenyl)- 1,2,3,4-tetrahydroisoquinolin-8-yl)methyl)- 2-(3-methyl-1,2,4-oxadiazol-5- yl)cyclopropanecarboxamide (mixture of 2 isomers)::US10568876, Example 86

SMILES COC[C@H]1CCC[C@H]1NC(=O)CN1CCc2c(C1)c(CNC(=O)C1CC1c1nc(C)no1)ccc2-c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=IRAQAQFABUTUKD-ACPFSOCMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435324   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435324(N-((2-(2-(((trans)-2- (methoxymethyl)cyclopentyl)a...)
Affinity DataIC50:  2.29E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent